Simon Gravel Ph.D.

Recent Publications

  1. Maples BK, Gravel S, Kenny EE, Bustamante CD. RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference. Am J Hum Genet. 2013 Aug 8;93(2):278-88.
  2. Botigué LR, Henn BM, Gravel S, Maples BK, Gignoux CR, Corona E, Atzmon G, Burns E, Ostrer H, Flores C, Bertranpetit J, Comas D, Bustamante CD. Gene flow from North Africa contributes to differential human genetic diversity in southern Europe. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11791-6.
  3. Kidd JM, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, Degenhardt JD, Brisbin A, Sheth V, Chen R, McLaughlin SF, Peckham HE, Omberg L, Bormann Chung CA, Stanley S, Pearlstein K, Levandowsky E, Acevedo-Acevedo S, Auton A, Keinan A, Acuña-Alonzo V, Barquera-Lozano R, Canizales-Quinteros S, Eng C, Burchard EG, Russell A, Reynolds A, Clark AG, Reese MG, Lincoln SE, Butte AJ, De La Vega FM, Bustamante CD. “Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation”. Am J Hum Genet. 2012 Oct 5;91(4):660-71. PMID: 23040495
  4. Tennessen JA, Bigham AW, O'Connor TD, Fu W, Kenny EE, Gravel S, McGee S, Do R, Liu X, Jun G, Kang HM, Jordan D, Leal SM, Gabriel S, Rieder MJ, Abecasis G, Altshuler D, Nickerson DA, Boerwinkle E, Sunyaev S, Bustamante CD, Bamshad MJ, Akey JM; Broad GO; Seattle GO; NHLBI Exome Sequencing Project. “Evolution and functional impact of rare coding variation from deep sequencing of human exomes”. Science. 2012 Jul 6;337(6090):64-9. PMID: 22604720
  5. Gravel S. “Population genetics models of local ancestry”. Genetics. 2012 Jun;191(2):607-19. PMID: 22491189
  6. Henn BM, Botigué LR, Gravel S, Wang W, Brisbin A, Byrnes JK, Fadhlaoui-Zid K, Zalloua PA, Moreno-Estrada A, Bertranpetit J, Bustamante CD, Comas D. “Genomic ancestry of North Africans supports back-to-Africa migrations”. PLoS Genet. 2012 Jan;8(1):e1002397. PMID: 22253600
  7. The 1000 Genomes Project Consortium. “An integrated map of genetic variation from 1,092 human genomes”. Nature 491, 56–65 (01 November 2012) doi:10.1038/nature11632
  8. Marth GT, Yu F, Indap AR, Garimella K, Gravel S, Leong WF, Tyler-Smith C, Bainbridge M, Blackwell T, Zheng-Bradley X, Chen Y, Challis D, Clarke L, Ball EV, Cibulskis K, Cooper DN, Fulton B, Hartl C, Koboldt D, Muzny D, Smith R, Sougnez C, Stewart C, Ward A, Yu J, Xue Y, Altshuler D, Bustamante CD, Clark AG, Daly M, DePristo M, Flicek P, Gabriel S, Mardis E, Palotie A, Gibbs R; 1000 Genomes Project. “The functional spectrum of low-frequency coding variation”. Genome Biol. 2011 Sep 14;12(9):R84. PMID: 21917140
  9. Gravel S, Henn BM, Gutenkunst RN, Indap AR, Marth GT, Clark AG, Yu F, Gibbs RA; 1000 Genomes Project, Bustamante CD. “Demographic history and rare allele sharing among human populations”. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11983-8. PMID: 21730125